TRPM8 in the negative regulation of TNFα expression during cold stress
نویسندگان
چکیده
منابع مشابه
TRPM8 in the negative regulation of TNFα expression during cold stress
Transient Receptor Potential Melastatin-8 (TRPM8) reportedly plays a fundamental role in a variety of processes including cold sensation, thermoregulation, pain transduction and tumorigenesis. However, the role of TRPM8 in inflammation under cold conditions is not well known. Since cooling allows the convergence of primary injury and injury-induced inflammation, we hypothesized that the mechani...
متن کاملthe effect of e-64 on the developmental competence of sheep cocs during in vitro maturation
in the present study, the effect of e-64 at different concentrations (0.5, 1, 5 and 10 µm) added to (1) the ivm medium on oocyte nuclear maturation and developmental competence of ovine oocytes, and (2) to the ivc medium on embryonic development of ovine embryos were investigated.
Cold stress regulation of gene expression in plants.
Cold stress adversely affects plant growth and development. Most temperate plants acquire freezing tolerance by a process called cold acclimation. Here, we focus on recent progress in transcriptional, post-transcriptional and post-translational regulation of gene expression that is critical for cold acclimation. Transcriptional regulation is mediated by the inducer of C-repeat binding factor (C...
متن کاملGene regulation during cold stress acclimation in plants.
Cold stress adversely affects plant growth and development and thus limits crop productivity. Diverse plant species tolerate cold stress to a varying degree, which depends on reprogramming gene expression to modify their physiology, metabolism, and growth. Cold signal in plants is transmitted to activate CBF-dependent (C-repeat/drought-responsive element binding factor-dependent) and CBF-indepe...
متن کاملTitle: Scraping through the Ice: Uncovering the Role of Trpm8 in Cold Transduction Running Title: Trpm8, a Cold Sensor
Title: Scraping through the ice: Uncovering the role of TRPM8 in cold transduction Running title: TRPM8, a cold sensor Authors: Daniel D. McCoy, Wendy M. Knowlton and David D. McKemy* Author Affiliations: Neurobiology, University of Southern California, Los Angeles, California 90089, USA *Corresponding author information: David D. McKemy 3641 Watt Way, HNB 228 University of Southern California ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Scientific Reports
سال: 2017
ISSN: 2045-2322
DOI: 10.1038/srep45155